A selection of intermediate (30%–70% association with cancer) and high-risk (above 70% association with cancer) autoantibody-mediated encephalitis39 40
| Autoantibody-mediated encephalitis | Related tumour |
| Intermediate-risk antibodies NMDAR AMPAR GABA A/B CASPR2 mGluR5 | Ovarian or extraovarian teratomas Small cell lung cancer, malignant thymoma Small cell lung cancer Malignant thymoma Hodgkin’s lymphoma |
| High-risk antibodies Hu CRMP5 Yo Ma2 | Small and non-small cell lung cancer, neuroendocrine tumours and neuroblastoma Small cell lung cancer and thymoma Small and non-small cell lung cancer, breast cancer Testicular cancer, non-small cell lung cancer |
AMPAR, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; CASPR2, contactin-associated protein-like 2; CRMP5, anticollapsing response-mediator protein-5; GABA, gamma-aminobutyric acid; mGluR5, metabotropic glutamate receptor 5; NMDAR, N-methyl-D-aspartate receptor; PCA2, Purkinje cell antigen 2.