Table 3

Predictors of fulminant onset COVID-19

Candidate predictor	Univariate model		Multi-variable model
Candidate predictor	Crude OR (95% CI)	P value	Adjusted OR (95% CI)	P value
Age
50–60 years	1.32 (1.00 to 1.75)	0.04	1.20 (0.88 to 1.63)	0.26
60–70 years	1.55 (1.19 to 2.02)	0.001	1.40 (1.03 to 1.90)	0.03
70–80 years	1.88 (1.40 to 2.53)	<0.001	1.77 (1.26 to 2.50)	0.001
>80 years	3.08 (2.06 to 4.60)	<0.001	2.76 (1.75 to 4.34)	<0.001
Vaccination status
Partial	0.64 (0.43 to 1.07)	0.03	0.67 (0.45 to 1.02)	0.06
Complete	0.68 (0.49 to 0.95)	0.02	0.61 (0.43 to 0.85)	0.004
Others
Male sex	1.16 (0.95 to 1.42)	0.14	1.10 (0.88 to 1.38)	0.39
Diabetes mellitus	1.34 (1.11 to 1.61)	0.002	1.11 (0.89 to 1.38)	0.35
Hypertension	1.55 (1.28 to 1.87)	<0.001	1.29 (1.03 to 1.61)	0.03
CKD	2.40 (1.53 to 3.73)	<0.001	1.77 (0.99 to 3.15)	0.05
Dialysis	1.68 (0.78 to 3.61)	0.18	0.54 (0.17 to 1.72)	0.30
CAD	1.52 (1.16 to 1.97)	0.002	1.25 (0.92 to 1.70)	0.15
COPD	2.37 (0.91 to 6.16)	0.08	1.70 (0.55 to 5.24)	0.36
Immuno-supressed	4.22 (1.44 to 12.41)	0.009	5.62 (1.69 to 18.71)	0.005
Chronic smoking	0.58 (0.21 to 1.56)	0.28	Excluded from multivariable model because of statistical insignificance (p>0.20 in univariate model)
Bronchial asthma	1.07 (0.65 to 1.74)	0.80
Vaccine type—Covaxin	0.48 (0.27 to 0.83)	0.009	Excluded from multivariable model because of collinearity with vaccination status
Vaccine type—Covishield	0.73 (0.53 to 1.02)	0.06

CAD, coronary artery disease; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease.