Table 3

Association between baseline factors and cardiorenal syndrome

Univariate analysisMultivariable analysis
OR (95% CI)P valueOR (95% CI)P value
Age1.03 (0.98 to 1.08)0.203
Male0.50 (0.16 to 1.62)0.247
Hypertension0.47 (0.14 to 1.56)0.218
Diabetes mellitus1.67 (0.52 to 5.37)0.390
CAD0.41 (0.13 to 1.34)0.142
Atrial fibrillation0.59 (0.19 to 1.88)0.371
LVEF1.01 (0.95 to 1.08)0.672
Heart rate0.99 (0.97 to 1.02)0.631
Cardiac output0.82 (0.55 to 1.22)0.326
MAP0.99 (0.96 to 1.03)0.725
TPR1.00 (0.99 to 1.00)0.996
E:E’0.88 (0.79 to 0.97)0.014*0.89 (0.78 to 1.00)0.06
RVSP0.97 (0.93 to 1.01)0.0921.02 (0.98 to 1.08)0.32
ECW:TBW × 1000.41 (0.22 to 0.76)0.004*
ECW:TBW ≥0.40.18 (0.05 to 0.67)0.01*0.12 (0.02 to 0.92)0.04*
Net output rate1.00 (0.99 to 1.01)0.919
BNP0.99 (0.99 to 1.00)0.007*0.99 (0.99 to 1.00)0.01*
NGAL1.00 (0.99 to 1.01)0.167
Creatinine1.00 (0.98 to 1.01)0.605
  • RVSP, right ventricular systolic pressure; ACEI, ACE inhibitor; ARB, angiotensin receptor blocker; BNP, B-type natriuretic peptide; CAD, coronary artery disease; E, early transmitral inflow velocity; E’, early diastolic mitral annular velocity; ECW, extracellular water; ECW:TBW, ratio of extracellular water to total body water; LVEF, left ventricular ejection fraction; MAP, mean arterial pressure; MRA, mineralocorticoid receptor antagonist; NGAL, neutrophil gelatinase-associated lipocalin; TPR, total peripheral resistance.