Table 3

Comparison of characteristics between those with painful SAT and those with painless SAT

Painless SAT (n=5)Painful SAT (n=6)Reference ranges
Age in years36.40 (12.47)50.5 (16.97)
Fever1 (20%)4 (66.67%)
Palpitation4 (80%)2 (55.55%)
Tremor3 (60%)2 (55.55%)
Time of onset since recovery from COVID-19 infection in days10.6 (5.65)*34.83 (9.26)
Severity of COVID-19 infectionMild/asymptomatic=0
Moderate=1
Severe=3
Mild/asymptomatic=1
Moderate=4
Severe=2
Required glucocorticoids during COVID-192 (40%)4 (66.67%)
Total T4 in µg/dL23.05 (5.9)18.4 (2.8)5.44–11.73
Total T3 in ng/dL186.33 (20.58)162.8 (21.6)78–136
Free T4 in ng/dL2.35 (0.85)2.19 (0.64)0.61–1.72
Free T3 in pg/mL6.6 (1.5)5.1 (0.6)2.2–4.2
ESR in mm/hour66.6 (21.2)72.8 (16.6)≤15 for men <50 years
≤22 for women <50 years and men ≥50 years
≤29 mm for women ≥50 years
Anti-TPO antibody positivity1 (20%)2 (33.33%)Positive: >35 IU/mL
CRP in mg/L212.33 (96.29)*69.12 (55.98)0–5
IL-6 in pg/mL110.00 (47.87)*50.41 (13.20)0–7
Absolute lymphocyte count1.59×103/μL*2.68×103/μL
Neutrophil-lymphocyte ratio2.8*1.83
Treatment required for SATNSAIDs=0
Glucocorticoids=0
NSAIDs=2
Glucocorticoids=4
Outcome at 3 monthsEuthyroidism=3
Subclinical hypothyroidism=2
Overt hypothyroidism=0
Euthyroidism=4
Subclinical hypothyroidism=1
Overt hypothyroidism (started on LT4)=1
Outcome at 6 monthsEuthyroidism=5
Subclinical hypothyroidism=0
Overt hypothyroidism=0
Euthyroidism=4
Subclinical hypothyroidism=1
Overt hypothyroidism (euthyroid with LT4 replacement)=1
  • *Denotes significant difference (p<0.05).

  • CRP, C reactive protein; ESR, erythrocyte sedimentation rate; IL-6, interleukin 6; LT4, levothyroxine; NSAIDs, non-steroidal anti-inflammatory drugs; SAT, subacute thyroiditis; TPO, thyroid peroxidase.