Table 2

Migraine risk and analyses by demographic characteristics and comorbidities among patients with or without keloids

Variables	Keloids cohort		Non-keloids cohort		Compared with non- keloids cohort
Variables	Migraine	Rate*	Migraine	Rate*	Crude HR (95% CI)	Adjusted HR† (95% CI)
Overall	103	1.81	323	0.55	3.57 (2.82 to 4.52)‡	2.29 (1.80 to 2.92)‡
Gender
Men	19	0.88	68	0.30	3.16 (1.85 to 5.40)‡	2.02 (1.17 to 3.51)§
Women	84	2.37	255	0.69	3.69 (2.84 to 4.79)‡	2.37 (1.81 to 3.10)‡
Stratify by age
18–49	84	1.71	213	0.42	4.35 (3.34 to 5.67)‡	2.65 (2.02 to 3.47)‡
>50	19	2.43	110	1.25	2.13 (1.29 to 3.49)§	1.46 (0.88-2.39)¶
Comorbidity**
No	10	0.48	41	0.12	4.21 (2.09 to 8.44)‡	3.49 (1.74 to 7.02)‡
Yes	93	2.55	282	1.06	2.57 (2.01 to 3.30)‡	2.16 (1.68 to 2.78)‡

*Rate, per 1000 person-years.
†Calculated by multivariate Cox proportional hazard regression model.
‡p<0.001.
§p<0.05.
¶P: non-significant.
**Patients with any examined comorbidities were classified as the comorbidity group.