Table 2

Migraine risk and analyses by demographic characteristics and comorbidities among patients with or without keloids

VariablesKeloids cohortNon-keloids cohortCompared with non- keloids cohort
MigraineRate*MigraineRate*Crude HR (95% CI)Adjusted HR† (95% CI)
Overall1031.813230.553.57 (2.82 to 4.52)‡2.29 (1.80 to 2.92)‡
Gender
 Men190.88680.303.16 (1.85 to 5.40)‡2.02 (1.17 to 3.51)§
 Women842.372550.693.69 (2.84 to 4.79)‡2.37 (1.81 to 3.10)‡
Stratify by age
 18–49841.712130.424.35 (3.34 to 5.67)‡2.65 (2.02 to 3.47)‡
>50192.431101.252.13 (1.29 to 3.49)§1.46 (0.88-2.39)¶
Comorbidity**
 No100.48410.124.21 (2.09 to 8.44)‡3.49 (1.74 to 7.02)‡
 Yes932.552821.062.57 (2.01 to 3.30)‡2.16 (1.68 to 2.78)‡
  • *Rate, per 1000 person-years.

  • †Calculated by multivariate Cox proportional hazard regression model.

  • ‡p<0.001.

  • §p<0.05.

  • ¶P: non-significant.

  • **Patients with any examined comorbidities were classified as the comorbidity group.