Table 3

Adjusted p value of multi-factor meta-regression analysis for the efficacy and safety of low dose ticagrelor in patients with acute coronary syndrome

CovariateMACELVEFLVDDMajor bleeding eventsMinor or minimal bleeding eventsNon-bleeding adverse eventsPAgRPRU
Average age0.800.490.200.970.200.850.420.74
Ticagrelor dose0.751.
  • Monte Carlo permutation test for meta-regression correction (permutations=10 000).

  • LVDD, Left ventricular end diastolic dimension; LVEF, Left ventricular ejection fraction; MACEs, Major adverse cardiac events; NR, Not reported; PAgR, platelet aggregation rate; PRU, Platelet reaction units.