Comparison of cortisol responses to ACTH at 30 and 60 min. These data show that there is a proportion of patients who will be diagnosed as AI if only 30 min sample was used
Group A—patients on steroids—total 120 patients (30.5%) | |||
60 min measurement | |||
Insufficient response | Normal response | ||
30 min measurement | Insufficient response | 51 (42.5%) | 8 (6.7%) (Late responders) |
Normal response | 0 (0.0%) | 61 (50.8%) | |
Group B—patients not on steroids—total 273 patients (69.5%) | |||
60 min measurement | |||
Insufficient response | Normal response | ||
30 min measurement | Insufficient response | 10 (3.7%) | 11 (4.0%) (Late responders) |
Normal response | 0 (0.0%) | 252 (92.3%) | |
All patients—total 393 patients (100%) | |||
60 min measurement | |||
Insufficient response | Normal response | ||
30 min measurement | Insufficient response | 61 (15.5%) | 19 (4.8%) (Late responders) |
Normal response | 0 (0.0%) | 313 (79.6%) |
AI, adrenal insufficiency.