Table 1

Dosages of antiviral agents for COVID-19

MedicationNormal renal function
(CrCl >50 mL/min)
Impaired renal function
(CrCl 25–50 mL/min)
Hemodialysis or CrCl <20 mL/min
Lopinavir/ritonavirLopinavir/ritonavir 400 mg/100 mg po every 12 hoursSame doseSame dose
HydroxychloroquineHydroxychloroquine 400 mg po 24 hoursData not availableData not available
Interferon-β1b0.25 mg/mL subcutaneous injection qEODData not availableData not available
Remdesivir200 mg loading dose on day 1 is given, followed by 100 mg intravenously once per day maintenance dosesSame doseSame dose
  • CrCl, creatinine clearance; po, by mouth.