Table 1

Clinical characteristics of participants

ParametersHealthy controls (n=49)COPD patients (n=84)P-value
Age (years)59.3±15.661.5±8.90.084
Sex (M:F)30/1955/290.327
BMI (kg/m2)* 25.7±2.521.3±2.8<0.001
Non-smoker,ex-smoker and current smoker3/15/315/32/470.527
Pack per year* 19.2±10.533.7±14.6<0.001
Number inhaled (ICS/LABA/LAMA)NA75/78/81NA
Pulmonary function
 FEV1 %predicted* 97.5±23.147.1±22.5<0.001
 FEV1/FVC ratio* 87.3±4.851.4±10.6<0.001
  • Parametric parameters were presented as mean±SD. Differences between healthy controls and COPD patients (*p<0.001). P<0.05 was considered significant. Body mass index (BMI)= weight (kg)/height (m2).

  • CAT, Chronic Obstructive Pulmonary Disease Assessment Test; COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; ICS, inhaled corticosteroids; LABA, long-acting β-adrenoceptor agonists; LAMA, a long-acting muscarinic antagonist; NA, not applicable.