Jadad Scoring for quality assessment of included trials
| Trials | Randomisation mentioned | Concealment of randomisation | Blinding | Appropriate blinding method | Reporting of withdrawals | Jadad score |
| Harrison et al 12 | Yes | Yes | Yes | Yes | Yes | 5 |
| Vajro et al 18 | Yes | Yes | Yes | Yes | Unclear | 4 |
| Nobili et al 16 | Yes | Unclear | Yes | Unclear | Yes | 3 |
| Nobili et al 17 | Yes | Yes | Yes | Yes | Yes | 5 |
| Sanyal et al 15 | Yes | Unclear | Yes | Yes | Yes | 4 |
| Foster et al 13 | Yes | Unclear | Yes | Yes | Unclear | 3 |
| Lavine et al 6 | Yes | Yes | Yes | Yes | Yes | 5 |
| Hoofnagle et al 14 | Yes | Unclear | Yes | Unclear | Yes | 3 |
| Aller et al 1 | Yes | Unclear | Yes | Unclear | Unclear | 2 |