Table 3

Risk of demyelinating diseases of the central nervous system, rather than multiple sclerosis, in patients with and without septicaemia, stratified by age, sex and comorbidity

VariableSepticaemia cohortComparison cohortAdjusted HR (95% CI)
EventPYsRateEventPYsRate
Age group
 <4547753 3796.24213 489 2020.606.41 (3.65 to 11.3)**
 45–6451531 0489.6293 283 6990.886.66 (3.98 to 11.2)**
 ≧6546798 4745.76865 579 8791.542.45 (1.65 to 3.62)**
Sex
 Female871 060 2548.21685 924 0561.154.43 (3.12 to 6.29)**
 Male571 022 6465.57686 428 7241.063.89 (2.63 to 5.75)**
Comorbidities
 No1151 893 5016.0713012 135 8491.073.95 (3.01 to 5.2)**
 Yes29189 39915.316216 9312.773.74 (1.50 to 9.27)*
  • Models adjusted for age, sex and comorbidities listed in table 1.

  • **p<0.01; **p<0.001.

  • PYs, person-years;Rate, incidence rate, per 100 000 person-years.