Univariate and multivariate logistic regression analyses for Gram-negative bacteraemic patients to investigate the association between patient characteristics, blood culture isolates and recruitment to OPAT (332 patients, 377 bacteraemic patients)
| Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
| OR (95% CI) | p Value* | OR (95% CI) | p Value* | |
| Age (years) | ||||
| 16–30 | Reference | 0.464 | Reference | 0.547 |
| 31–50 | 1.56 (0.17 to 14.11) | 1.67 (0.17 to 16.42) | ||
| 51–70 | 1.03 (0.12 to 8.94) | 0.97 (0.10 to 9.12) | ||
| >70 | 0.47 (0.05 to 4.77) | 0.53 (0.05 to 5.76) | ||
| Gender | ||||
| Female | Reference | 0.442 | Reference | 0.614 |
| Male | 0.67 (0.24 to 1.88) | 0.76 (0.25 to 2.25) | ||
| Specialty | ||||
| Medicine | Reference | 0.242 | Reference | 0.228 |
| Surgery | 0.30 (0.04 to 2.28) | 0.28 (0.03 to 2.23) | ||
| Site of infection | ||||
| Urinary tract | Reference | 0.341 | Reference | |
| Skin and soft tissue | 4.69 (0.49 to 44.82) | 5.94 (0.39 to 89.49) | ||
| Other | 0.85 (0.29 to 2.49) | 0.73 (0.22 to 2.41) | 0.344 | |
| Escherichia coli | ||||
| No | Reference | 0.987 | Reference | 0.756 |
| Yes | 1.01 (0.36 to 2.83) | 1.21 (0.37 to 3.95) | ||
| ESBL production | ||||
| Negative | Reference | 0.001 | Reference | 0.002 |
| Positive | 6.15 (2.13 to 17.75) | 5.85 (1.94 to 17.62) | ||
One patient with obstetrics and gynaecology specialty was excluded.
Generalised estimating equations were used to adjust for multiple episodes for some patients.
*Joint Wald test.
ESBL, extended-spectrum β-lactamase; OPAT, outpatient parenteral antibiotic treatment.