Table 3

Quality of life (QOL) and behavioural measures

Normal cognitive performance (n=22)Cognitively impaired
(n=40)
Mean (SD)Mean (SD)Mean difference (95% CI)p Value
Functional assessment of multiple sclerosis117.1 (23.7)90.9 (30.9)26.12 (10.95 to 41.29)0.001
Patient activation measure -1364.9 (13.1)61.8 (17.0)3.04 (−5.35 to 11.44)0.471
EuroQOL five dimension questionnaire8.6 (2.6)11.8 (3.3)−3.18 (−4.82 to −1.55)<0.001
Unidimensional Self-Efficacy scale for multiple sclerosis20.3 (5.2)17.4 (6.8)2.86 (−0.45 to 6.18)0.089
Multiple sclerosis neuropsychological questionnaire27.1 (10.5)35.6 (12.2)−8.56 (−14.73 to −2.38)0.007
Hospital anxiety and depression scale (depression)7.2 (3.6)9.0 (3.3)−1.80 (−3.60 to 0.01)0.050
Hospital anxiety and depression scale (anxiety)7.5 (5.2)9.2 (4.7)−1.65 (−4.24 to 0.94)0.208
Fatigue severity scale45.81 (9.5)50.4 (11.9)−4.54 (−10.54 to 1.46)0.136