Table 1

Summary of characteristics for the lung cancer and resistant smokers

VariableLung cancer patients (n = 446)Healthy control smokers (n = 484)p Value
Characteristic
    Male53%60%0.007
    Age (years)69 (10)60 (10)<0.001
    Height (cm)167 (0.08)170 (0.09)<0.001
    Weight (kg)69 (15)79 (15)<0.001
    History of COPD29%5%<0.001
Smoking history
    Non-smokers (%)7%0
    Current smoking (%)35%48%<0.001
    Age started (years)18 (4)17 (3)0.18
    Years smoked41 (12)35 (11)<0.001
    Pack-years41 (25)40 (19)0.28
    Cigarettes/day20 (10)24 (11)<0.001
History of other exposures
    In utero smoke exposure18%17%0.45
    Mother smoked in childhood37%41%0.03
    Home ETS exposure as adult79%58%<0.001
    Work ETS exposure86%63%<0.001
    Work dust exposure63%47%<0.001
    Work fume exposure41%38%0.16
    Asbestos exposure23%16%0.02
Family history
    COPD33%28%0.12
    Lung cancer19%9%<0.001
Lung function
    FEV1 (litres)1.86 (0.48)2.86 (0.68)<0.001
    FEV1 % predicted73%99%<0.001
    FEV1/FVC64 (13)78 (7)<0.001
    Spirometric COPD*51%0%<0.001
  • Values are frequency (given as %) or mean (SD).

  • *According to GOLD 2+ criteria (FEV1/FVC < 70% and FEV1 % predicted ⩽ 80%).

  • COPD, chronic obstructive pulmonary disease; ETS, environmental tobacco smoke; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity.