Table 3

 Risk stratification model to predict progression of monoclonal gammopathy of undetermined significance (MGUS) to myeloma or related disorders

Risk groupNumber of patientsRelative riskAbsolute risk of progression at 20 years (%)Absolute risk of progression at 20 years accounting for death as a competing risk (%)
Reproduced with permission from Kyle and Rajkumar.3
Low risk serum M-protein <15 g/l, IgG type, normal free light chain ratio (0.26–1.65)449152
Low-intermediate risk (any one risk factor abnormal)4205.42110
High-intermediate risk (any two risk factors abnormal)22610.13718
High risk (all three risk factors abnormal)5320.85827