Table 1

 Pharmacokinetics of cocaine according to the route of administration

Route of administrationOnset of actionPeak effectDuration of action
Inhalation (smoking)3–5 seconds1–3 minutes5–15 minutes
Intravenous10–60 seconds3–5 minutes20–60 minutes
Intranasal or mucusal1–5 minutes15–20 minutes60–90 minutes
GastrointestinalUp to 20 minutesUp to 90 minutesUp to 180 minutes