Causes of lactic acidosis
| Type A (anaerobic/hypoxic) | Type B (aerobic) |
|---|---|
| Adapted from Stacpoole et al.80 | |
| Shock: | Systemic disease: |
| Cardiogenic | Diabetes |
| Endotoxic | Neoplasia |
| Hypovolaemic | Liver disease |
| Cardiac failure | Drugs/toxins: |
| Biguanides | |
| Asphyxia | Ethanol |
| Methanol | |
| Carbon monoxide poisoning | Salicylates |
| Inborn errors of metabolism: | |
| Type 1 glycogen storage disease | |
| Fructose 1,6-diphosphatase deficiency | |