Diagnostic criteria for diabetic ketoacidosis (DKA) and hyperglycaemic hyperosmolar state (HHS)
DKA | ||||
---|---|---|---|---|
Mild | Moderate | Severe | HHS | |
*Formula: 2×{[Na+]+[K+]}+[urea]+[glucose]. | ||||
†Formula: [Na+]–([Cl−]+[HCO3−]) (mmol/l). Table largely adapted from Kitabchi et al.5 | ||||
Plasma glucose (mmol/l | ⩾14 | ⩾14 | ⩾14 | ⩾30 |
Arterial pH | 7.25–7.35 | 7.0–⩽7.24 | <7.0 | >7.3 |
Serum bicarbonate (mmol/l) | 15–18 | 10–14 | <10 | >15 |
Urine ketones | ⩾++ | ⩾++ | ⩾++ | ⩽+ |
Plasma ketones | ⩾++ | ⩾++ | ⩾++ | ⩽+ |
Total osmolality (mOsm/kg)* | Variable | Variable | Variable | ⩾340 |
Anion gap† | >10 | >12 | >12 | <12 |
Level of consciousness | Alert | Alert/drowsy | Stupor/coma | Stupor/coma |