Table 3

Antituberculosis drugs

DrugDosage (mg/kg/day)Side effects
Isoniazid5–10Resistance not uncommon, hepatitis, peripheral neuropathy in risk groups
Rifampicin10–20Microsomal enzyme induction leading to drug interactions, colours urine, hepatitis, flu-like syndrome (vomiting, fever, myalgia), skin rash
Pyrazinamide20–35Hepatitis, uricaemia, arthralgia
Ethambutol15–25Retrobulbar neuritis. Contraindicated in children <5 years who cannot report eye symptoms