Table 1

The original Duke’s criteria for the diagnosis of endocarditis.6 Two major, one major and three minor, or five minor criteria are necessary for the diagnosis of endocarditis

Major Duke’s criteriaMinor Duke’s criteria
1. Positive blood cultures with a typical organism1. Predisposing cardiac condition
2. Evidence of endocardial involvement from echocardiography2. Fever
3. Vascular phenomena: emboli, mycotic aneurysm, Janeway’s lesion
4. Immunological phenomena: glomerulonephritis, splinter haemorrhages, Roth’s spots, Osler’s nodes
5. Positive blood cultures with organism consistent but not typical for endocarditis
6. Positive echocardiography with findings consistent with but not typical for endocarditis