Table 1

 Some commonly used medications with moderate to high anticholinergic properties and alternative suggestions

Type of medicationAlternatives with less delirogenic risk
SSRI, selective serotonin reuptake inhibitor; TCA, tricyclic antidepressant.
Antidepressant (for example, TCA, tertiary)Trazodone, SSRI, TCA (secondary amine)
Antihistamine (for example, diphenhydramine)Second generation antihistamine (for example, loratadine)
Antiparkinsonian (for example, benztropine, trihexyphenidyl)Levodopa
Gastrointestinal agents, for example:
    (A) Cimetidine, ranitidineProton pump inhibitor
    (B) DimenhydrinateDomperidone
Antispasmodic (for example, oxybutynin)Tolterodine
Low potency antipsychotic (for example, chlorpromazine, thioridazone)Haloperidol, atypical antipsychotic