Table 1

Drug therapy in SLE

NSAIDsAntimalarialsCorticosteroidsCytotoxic agents
+, Usually beneficial; –, not beneficial; ?, dubious/controversial; *, widely prescribed though evidence regarding its efficacy is largely lacking. CNS, central nervous system.
Malaise++
Fever++
Serositis++
Arthralgia+++
Arthritis++++
Myalgia+++
Myositis++
Malar/discoid rash++
Pneumonitis++
Carditis++
Vasculitis++
CNS?*?
Renal++
Haemolytic anaemia++
Thrombocytopenia++
Raynauds??
Alopecia??