Additional clinical features in 15 patients with coeliac disease and metabolic bone disease
Patient |
Femur T score | % change spine/year | % change femur/year | Bone biopsy | Comments | Other abnormalities |
1 | −3.1 | 21.3 | 15.7 | Osteomalacia | Initially diagnosed as Paget's disease | MCV 114 |
2 | −2.4 | 18.4 | 10.3 | Osteomalacia | Iron deficiency | |
3 | −4.6 | 11.9 | 6.1 | Osteomalacia | Rheumatoid disease | |
4 | 1.8 | Tertiary hyperparathyroidism | Parathyroid adenoma | |||
5 | −2.9 | B-12 and folate deficiency | ||||
6 | −3.2 | −2 | 12.6 | Normal | Iron deficiency | |
7 | −3.2 | Previous Colle's fracture | B-12 and folate deficiency | |||
8 | −4.15 | Steroid and diet resistant coeliac disease | Iron, B-12, and folate deficiency | |||
9 | −2.08 | B-12 and folate deficiency; diabetes | ||||
10 | −0.2 | Iron and folate deficiency | ||||
11 | −3.6 | 0.9 | 4.9 | Osteoporosis | Late menarche; early menopause | Macrocytosis |
12 | −3.48 | 1.1 | 4.2 | Osteoporosis | Unresponsive iron deficiency | |
13 | −2.2 | 7.7 | 8.0 | Iron deficiency | ||
14 | −3.1 | −0.9 | −0.3 | Failure to comply with gluten-free diet | Iron deficiency | |
15 | −3.2 | 4.1 | −5.4 | BMD improved on cyclical etidronate |
BMD, bone mineral density; MCV, mean corpuscular volume.