Features and treatment of Addison's disease
| Common symptoms and signs | Laboratory features |
| Anorexia | Hyponatraemia |
| Weakness | Hyperkalaemia |
| Fatigue | Uraemia |
| Nausea and vomiting | Metabolic acidosis |
| Postural dizziness | Hypercalcaemia |
| Weight loss | Normochromic normocytic anaemia |
| Hypotension | Eosinophilia |
| Pigmentation | Lymphocytosis |
| Emergency treatment | Maintenance therapy |
| Measure plasma cortisol | Primary adrenal failure: |
| Intravenous hydrocortisone 100 mg with 0.9% saline | Hydrocortisone 15–20 mg am, 5–10 mg at 4 pm or |
| Hydrocortisone 15–20 mg am, 5 mg at noon, 5 mg at 4 pm | |
| and | |
| Fludrocortisone 0.05–2 mg am | |
| Secondary adrenal failure: | |
| Hydrocortisone as above |