Table 1

Summary of six prospective controlled studies on lupus flares during pregnancy

Authors Patients (n) Pregnancies (n) Controls Use of disease activity scale (yes/no) Quantified measure of flares (yes/no) Results
Lockshinet al 8(1984)2833MatchedYesNoNo differences in flares
Mintz et al 9(1986)75102UnmatchedNoNoNo differences in flares
Urowitz et al 10(1993)4679MatchedYesYesNo differences in flares
Wong et al 11(1991)2229UnmatchedNoNoIncreased flares in pregnancy
Petri et al 12(1991)3740UnmatchedYesYesIncreased flares in pregnancy than controls and after delivery
Post-delivery course
Ruiz-Irastorza et al 13(1996)6878MatchedYesYesIncreased flares in pregnancy than controls and after delivery
Post-delivery course