Causes of hypercalcaemia in myeloma
| Myeloma bone disease |
| Postulated chemical mediators for osteoclast activating factor include1 2 |
| Interleukin-1 |
| Interleukin-6 |
| Tumour necrosis factor-α |
| Lymphotoxin |
| Colony stimulating factors |
| Unidentified factors |
| PTH-rP3 |
| Abnormal calcium binding globulins4 5 |
| Coincident presence of another disease causing hypercalcaemia including primary hyperparathyroidism6 |
PTH-rP = parathyroid hormone related peptide.