Table 4

 Trials of GP IIb/IIIa inhibitors in acute coronary syndromes

Trial (ref) Patients (n) Year of commencement Duration of infusion (h) Unstable angina (%) Non-Q wave MI (%)
PRISM (43)32321994487525
PRISM-PLUS (46)1915199448–605545
PARAGON (47)2282199572–120
PURSUIT (48)10 9481995725545
  • PRISM: Platelet Receptor Inhibition in Ischaemic Syndrome Management; PRISM-PLUS: Platelet receptor Inhibition in Ischaemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms; PARAGON: Platelet IIb/IIIa Antagonism for the Reduction of Acute coronary syndrome events in a Global Organisation Network; PURSUIT: Platelet Glyoprotein IIb/IIIa in Unstable angina: Receptor Suppression Using Integrilin Therapy. In PARAGON, exact numbers of non-Q wave MI were not given.