RT Journal Article
SR Electronic
T1 Impact of socioeconomic deprivation on mortality in people with haemorrhagic stroke: a population-based cohort study
JF Postgraduate Medical Journal
JO Postgrad Med J
FD The Fellowship of Postgraduate Medicine
SP 501
OP 505
DO 10.1136/postgradmedj-2015-133663
VO 92
IS 1091
A1 McCormick, Jacquelyn
A1 Chen, Ruoling
YR 2016
UL http://pmj.bmj.com/content/92/1091/501.abstract
AB Purpose Socioeconomic deprivation (SED) has an effect on many health outcomes, including ischaemic stroke; however, its impact on mortality after haemorrhagic stroke remains unclear, particularly in the long run. We examined this association in a multiethnic population in the UK.Design We examined data from 782 patients with first-ever haemorrhagic stroke, collected by the South London Stroke Register from 1995 to 2011. SED was defined as the quartile with the highest Carstairs scores, and was analysed in relation to mortality after stroke in a multivariate-adjusted Cox regression model.Results In a follow-up of 17 years, 498 patients died. Compared with the first quartile of Carstairs score (the least deprived), the multivariate-adjusted HRs for 17-year mortality in patients in the second, third and fourth quartiles were 0.94 (95% CI 0.72 to 1.23), 1.17 (95% CI 0.90 to 1.52) and 1.36 (95% CI 1.04 to 1.78), overall p=0.04. The SED gradient association remained in patients with intracerebral haemorrhagic stroke, while in patients with subarachnoid haemorrhagic stroke the corresponding HRs were 2.62 (95% CI 1.22 to 5.64), 3.03 (95% CI 1.49 to 6.18) and 1.83 (95% CI 0.87 to 3.83), respectively. Results of 10-year mortality showed similar patterns, although the association of deprivation with 1-year mortality was not significant.Conclusions There is a significant impact of SED on long-term mortality after haemorrhagic stroke. The reasons for this survival inequality must be explored to reduce mortality in patients with haemorrhagic stroke.