RT Journal Article SR Electronic T1 Cardiopulmonary exercise testing and its application JF Postgraduate Medical Journal JO Postgrad Med J FD The Fellowship of Postgraduate Medicine SP 675 OP 682 DO 10.1136/hrt.2007.121558 VO 83 IS 985 A1 Albouaini, Khaled A1 Egred, Mohaned A1 Alahmar, Albert A1 Wright, David Justin YR 2007 UL http://pmj.bmj.com/content/83/985/675.abstract AB Cardiopulmonary exercise testing CPET has become an important clinical tool to evaluate exercise capacity and predict outcome in patients with heart failure and other cardiac conditions. It provides assessment of the integrative exercise responses involving the pulmonary, cardiovascular and skeletal muscle systems, which are not adequately reflected through the measurement of individual organ system function. CPET is being used increasingly in a wide spectrum of clinical applications for evaluation of undiagnosed exercise intolerance and for objective determination of functional capacity and impairment. This review focuses on the exercise physiology and physiological basis for functional exercise testing and discusses the methodology, indications, contraindications and interpretation of CPET in normal people and in patients with heart failure.