PT - JOURNAL ARTICLE AU - Albouaini, Khaled AU - Egred, Mohaned AU - Alahmar, Albert AU - Wright, David Justin TI - Cardiopulmonary exercise testing and its application AID - 10.1136/hrt.2007.121558 DP - 2007 Nov 01 TA - Postgraduate Medical Journal PG - 675--682 VI - 83 IP - 985 4099 - http://pmj.bmj.com/content/83/985/675.short 4100 - http://pmj.bmj.com/content/83/985/675.full SO - Postgrad Med J2007 Nov 01; 83 AB - Cardiopulmonary exercise testing CPET has become an important clinical tool to evaluate exercise capacity and predict outcome in patients with heart failure and other cardiac conditions. It provides assessment of the integrative exercise responses involving the pulmonary, cardiovascular and skeletal muscle systems, which are not adequately reflected through the measurement of individual organ system function. CPET is being used increasingly in a wide spectrum of clinical applications for evaluation of undiagnosed exercise intolerance and for objective determination of functional capacity and impairment. This review focuses on the exercise physiology and physiological basis for functional exercise testing and discusses the methodology, indications, contraindications and interpretation of CPET in normal people and in patients with heart failure.