PT  - JOURNAL ARTICLE
AU  - Kumar, D
AU  - Tandon, R K
TI  - Fatigue in cholestatic liver disease—a perplexing symptom
AID  - 10.1136/pmj.78.921.404
DP  - 2002 Jul 01
TA  - Postgraduate Medical Journal
PG  - 404--407
VI  - 78
IP  - 921
4099  - http://pmj.bmj.com/content/78/921/404.short
4100  - http://pmj.bmj.com/content/78/921/404.full
SO  - Postgrad Med J2002 Jul 01; 78
AB  - Fatigue is an important symptom and a quality of life determinant in patients with cholestatic liver disease. The pathogenesis of fatigue is obscure, although alterations in central neurotransmission and peripheral muscle dysfunction have been incriminated. No effective treatment is available at present. The available literature on fatigue in cholestatic liver disease is reviewed.