RT Journal Article
SR Electronic
T1 Prostate cancer
JF Postgraduate Medical Journal
JO Postgrad Med J
FD The Fellowship of Postgraduate Medicine
SP 590
OP 595
DO 10.1136/pmj.78.924.590
VO 78
IS 924
A1 Mazhar, D
A1 Waxman, J
YR 2002
UL http://pmj.bmj.com/content/78/924/590.abstract
AB It is a paradigm in cancer treatment that early detection and treatment improves survival. However, although screening measures lead to a higher rate of detection, for small bulk localised prostate cancer it remains unclear whether early detection and early treatment will lead to an overall decrease in mortality. The management options include surveillance, radiotherapy, and radical prostatectomy but there is no evidence base to evaluate the benefits of each approach. Advanced prostate cancer is managed by hormonal therapy. There have been major changes in treatment over the last two decades with the use of more humane treatment and developments in both chemotherapy and radiation. In this article we review the natural history and management of prostate cancer.