RT Journal Article
SR Electronic
T1 Effect of treatment with botulinum toxin on spasticity.
JF Postgraduate Medical Journal
JO Postgrad Med J
FD The Fellowship of Postgraduate Medicine
SP 208
OP 210
DO 10.1136/pgmj.65.762.208
VO 65
IS 762
A1 Das, T. K.
A1 Park, D. M.
YR 1989
UL http://pmj.bmj.com/content/65/762/208.abstract
AB Botulinum toxin, a product of Clostridium botulinum, produces presynaptic neuromuscular block by preventing release of acetylcholine from nerve endings. The toxin was injected directly into the skeletal muscles of six patients with severe spasticity due to stroke-related hemiplegia. It produced both subjective and objective improvement. The toxin injections were well tolerated and no significant side effect was reported.