PT  - JOURNAL ARTICLE
AU  - Das, T. K.
AU  - Park, D. M.
TI  - Effect of treatment with botulinum toxin on spasticity.
AID  - 10.1136/pgmj.65.762.208
DP  - 1989 Apr 01
TA  - Postgraduate Medical Journal
PG  - 208--210
VI  - 65
IP  - 762
4099  - http://pmj.bmj.com/content/65/762/208.short
4100  - http://pmj.bmj.com/content/65/762/208.full
SO  - Postgrad Med J1989 Apr 01; 65
AB  - Botulinum toxin, a product of Clostridium botulinum, produces presynaptic neuromuscular block by preventing release of acetylcholine from nerve endings. The toxin was injected directly into the skeletal muscles of six patients with severe spasticity due to stroke-related hemiplegia. It produced both subjective and objective improvement. The toxin injections were well tolerated and no significant side effect was reported.