RT Journal Article
SR Electronic
T1 Failure of anti-hypertensive drugs to control blood pressure rise with isometric exercise in hypertension.
JF Postgraduate Medical Journal
JO Postgrad Med J
FD The Fellowship of Postgraduate Medicine
SP 552
OP 555
DO 10.1136/pgmj.57.671.552
VO 57
IS 671
A1 O'Hare, J. A.
A1 Murnaghan, D. J.
YR 1981
UL http://pmj.bmj.com/content/57/671/552.abstract
AB Isometric exercise causes a substantial rise in BP in normotensive and untreated hypertensives. The authors studied the isometric hand-grip test in 5 groups of treated hypertensives, namely beta-blockers, beta-blockers + diuretics, beta-blockers + diuretics + vasodilators, alpha-methyldopa alone and labetalol. All groups showed a substantial rise in both systolic and diastolic BP, and the increments in BP differed little from that in normotensives. Some patients, despite multiple therapy, achieved increments of up to 60 mmHg from rest. Treated hypertensives with cardiac and cerebro-vascular disease are at risk performance isometric exercise.