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Original research
Relationship between obstructive sleep apnoea syndrome and silent brain infarction
  1. Vusal Nacafaliyev1,
  2. Pınar Ortan2,
  3. Sevgi Sidika Sayin1
  1. 1Department of Neurology, University of Health Sciences Izmir Bozyaka Education and Research Hospital, Izmir, Turkey
  2. 2Neurology, University of Health Sciences Izmir Bozyaka Education and Research Hospital, Izmir, Turkey
  1. Correspondence to Professor Pınar Ortan, Neurology, University of Health Sciences Izmir Bozyaka Education and Research Hospital, Izmir, Izmir, Turkey; kurceren{at}hotmail.com

Abstract

Background The relationship between obstructive sleep apnea syndrome (OSAS) and ischaemic stroke is less known.

Objectives This study aimed to investigate the relationship between OSAS and silent brain infarcts (SBI).

Methods Patients who applied to our clinic with the complaint of snoring, respiratory arrest during sleep, that underwent polysomnography were included. All patients were undergone cranial magnetic resonance imaging to detect SBI.

Results SBI was found in 176 (51.5%) of 270 patients in the group with OSAS and 94 (34.8%) patients without OSAS. The patients were evaluated according to their Apnea–Hypopnea Index(AHI) ratio, and those with were found to be significant in terms of SBI. SBI was detected in 56.56% in the moderate and severe (AHI ˃15) stage group and 39.94% in the normal and mild (AHI ≤15) OSAS group (p=0.009).

Conclusions SBI was found to be significantly higher in patients with moderate and severe stage OSAS compared to the normal and mild OSAS group. Desaturations during sleep may influence the formation of these infarcts. Therefore, this study reported that patients with moderate and severe sleep apnea syndrome may have a higher risk of developing ischaemic cerebrovascular disease and that the treatment of these patients should be planned in this respect.

  • stroke medicine
  • neurophysiology
  • neuroradiology
  • respiratory medicine

Data availability statement

Data are available on reasonable request.

http://dx.doi.org/10.1136/pmj-2022-141911

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    Data availability statement

    Data are available on reasonable request.

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    Footnotes

    • Contributors PO planned this study and is the guarantor. VN facilitated the execution of the study. SSS took part in the interpretation of polysomnography.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.