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Retrospective analysis of the appendiceal neoplasms: sampling technique may influence neoplasm detection
  1. Gizem Issin1,
  2. Fatih Demir1,
  3. Hasan Aktug Simsek2,
  4. Diren Vuslat Cagatay1,
  5. Mahir Tayfur1,
  6. Mecdi Gurhan Balci1
  1. 1Department of Pathology, Erzincan Binali Yildirim University, Mengucek Gazi Training and Research Hospital, Erzincan, Turkey
  2. 2Department of Pathology, Eskisehir City Hospital, Eskisehir, Turkey
  1. Correspondence to Dr Gizem Issin, Pathology, Erzincan Binali Yildirim University, Mengucek Gazi Training and Research Hospital, erzincan, erzincan, Turkey; gizemissin{at}gmail.com

Abstract

Background and aims Appendiceal neoplasms are uncommon entities that are usually determined incidentally during the histopathological examination. Different techniques used for the macroscopic sampling of appendectomy material may affect the determinating neoplasms.

Materials and methods H&E-stained slides of 1280 cases who underwent appendectomy between 2013 and 2018 were reviewed retrospectively for histopathological features.

Results Neoplasms were determined in 28 cases (3.09%); 1 lesion was observed in the proximal part of the appendix, 1 covering the entire length from proximal to distal and 26 in the distal part. In the 26 cases that observed in the distal part, the lesion was seen on both sides of the longitudinal section of the distal appendix in 20 cases, while it was seen on only one distal longitudinal section in the remaining 6 cases.

Conclusion The vast majority of appendiceal neoplasms are seen in the distal part of the appendix, and, in some cases, neoplasms might be seen on only one side of the distal section. Sampling only one-half of the distal part of the appendix, where tumours are most often observed, could result in some neoplasms being missed. Therefore, sampling the whole distal part would be more beneficial to determine small diameter tumours that do not create macroscopic findings.

  • gastrointestinal tumours
  • colorectal surgery
  • pathology

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All data relevant to the study are included in the article or uploaded as supplementary information. Not applicable

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Data availability statement

All data relevant to the study are included in the article or uploaded as supplementary information. Not applicable

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Footnotes

  • Contributors GI contributed to conceptualisation, data collection, literature review, writing-original draft preparation. She is guarantor. FD contributed to writing-original draft preparation, figure illustration. DVC, MT contributed to histopathologic examination, data collection. HAS and MGB contributed to reviewing and editing, supervision. All authors approved final version.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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