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Secondary haemophagocytic lymphohistiocytosis (HLH) triggered by Salmonella typhi
  1. Navneet Arora1,
  2. Neeraj Singla2,
  3. Aleena Jain3,
  4. Prashant Sharma4,
  5. Navneet Sharma1
  1. 1Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India
  2. 2PGIMER, Chandigarh, India
  3. 3Internal Medicine, Chandigarh, India
  4. 4Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
  1. Correspondence to Dr Neeraj Singla, PGIMER, Chandigarh 29751, India; neerajsingladr{at}gmail.com

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A 19-year-old woman with no significant medical history presented to the emergency room with high-grade fever (up to 103°F), generalised weakness, loose stools and vomiting for 4 days. She was pale on examination and had a blood pressure of 100/60 mm Hg, a pulse rate of 114 beats/min and maintained 97% of oxygen saturation on room air. Ultrasonography of the abdomen was suggestive of hepatosplenomegaly. Laboratory investigations revealed pancytopenia, serum ferritin of 1690 ng/mL, and bone marrow examination was suggestive of presence …

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Footnotes

  • Contributors NA: writing the original manuscript and patient care. NSingla: manuscript supervision, expert guidance and patient care. AJ: bone marrow imaging, reporting, figure legends. PS: bone marrow imaging, expert guidance and figure legends. NSharma: expert guidance and patient management.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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