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Do subtle findings on chest X-ray predict worse outcomes for paediatric asthma?
  1. Michael Abeles1,
  2. Meredith Akerman2,
  3. Claudia Halaby1,
  4. Melodi Pirzada1
  1. 1Pediatric Pulmonology, NYU Winthrop Hospital, Mineola, New York, USA
  2. 2Biostatistics, NYU Winthrop Hospital, Mineola, New York, USA
  1. Correspondence to Dr Michael Abeles, Pediatric Pulmonology, NYU Winthrop Hospital, Mineola, NY 11501, USA; mbabeles{at}


Background Asthma, a common childhood condition, often presents with chronic cough. While evaluating for chronic cough, many specialists obtain a baseline chest radiograph (CR) to assess for other causes. Usually read as ‘normal’, sometimes CRs will reveal evidence of airway inflammation in the form of subtle findings, such as ‘increased interstitial markings’ or ‘peribronchial thickening’. There is sparse literature in the outpatient setting correlating findings on baseline CRs with adverse outcomes such as systemic steroid use, emergency department (ED) visit or hospitalisation.

Methods This was a retrospective study of patients seen at our institution’s Pediatric Pulmonology outpatient clinic. We reviewed the charts of all new patients aged 0–18 years who presented between January 2015 and December 2017. Patients were included if they were diagnosed with asthma, had a CR after the initial visit and were followed up at least twice. Adverse outcomes include systemic steroid use, ED visit or hospitalisation.

Results 130 subjects were included. 89 subjects had clear CRs and 41 subjects had CRs with airway inflammation. Overall events were higher in the airway inflammation group (22.5% vs 46.3%, respectively, p<0.0058). There were no significant differences between in terms of oral corticosteroid use or hospitalisations. There was a significant difference between the two groups in terms of ED visits (2.2% vs 14.6%, respectively, p=0.0121).

Conclusion This study shows a positive correlation between airway inflammation findings on baseline CR and subsequent ED visits in patients with asthma.

  • asthma
  • paediatric thoracic medicine

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  • Contributors All authors contributed to the manuscript. All authors were involved in the design of the study. MiAb collected the data. MeAk performed statistical analysis. MiAb, CH and MP wrote the manuscript and all authors were involved in the final approval of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Ethics approval This study was approved by the local Institutional Review Board.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement All data relevant to the study are included in the article or uploaded as online supplemental information. Data are de-identified participant data included in the article as tables.

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