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Diagnostic and prognostic value of biomarkers in acute myocardial infarction
  1. Yuqi Chen,
  2. Yifei Tao,
  3. Lan Zhang,
  4. Weiting Xu,
  5. Xiang Zhou
  1. Department of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou, China
  1. Correspondence to Xiang Zhou, Department of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou, China; zhou-xiang{at}suda.edu.cn; Weiting Xu, Department of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou, China; xuwt1968{at}aliyun.com

Abstract

The incidence of acute myocardial infarction (AMI) has been increasing rapidly in recent years, seriously endangering human health. Cardiac biomarkers play critical roles in the diagnosis and prognosis of AMI. Troponin is a highly sensitive and specific biomarker for AMI diagnosis and can independently predict adverse cardiac events. Other biomarkers such as N-terminal B-type natriuretic peptide and C reactive protein are also valuable predictors of cardiovascular prognosis. Recently, several novel biomarkers have been identified for the diagnosis and risk assessment in patients with AMI. A multibiomarker approach can potentially enhance the diagnostic accuracy and provide more information for the early risk stratification of AMI. In this review, we will summarise the biomarkers discovered in recent years and focus on their diagnostic and prognostic value for patients with AMI.

  • acute myocardial infarction
  • biomarkers
  • diagnosis
  • prognosis

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Footnotes

  • YC and YT contributed equally.

  • Contributors YC, YT and LZ wrote the manuscript. WX and XZ revised the manuscript.

  • Funding This study was financially supported by the National Natural Science Foundation of China (no. 81770370) and Scientific Research Program for Young Talents of China National Nuclear Corporation (no. 51001).

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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