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Blisters on the sun-exposed area: as a clue for underlying hepatitis C virus infection
  1. Ankur Guliani1,
  2. Krishna Jha1,
  3. Divya Aggarwal2,
  4. Bishan Dass Radotra2,
  5. Atul Rana3,
  6. Muthu Sendhil Kumaran1
  1. 1 Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
  2. 2 Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
  3. 3 Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
  1. Correspondence to Dr Muthu Sendhil Kumaran, Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India; drsen_2000{at}yahoo.com

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A 45-year-old woman presented with recurrent fluid-filled blisters over hands, feet, forearm and face for the last 5 years. Blisters ruptured with minor trauma or spontaneously after 6–7 days. Lesions aggravated on exposure to sunlight. There was a history of dark-coloured urine. Clinical examination revealed multiple well-defined superficial moist erosions over dorsal aspect of hands, feet, forearm and face healing with postinflammatory hypopigmentation along with scars. Additionally, she had hypertrichosis and melisma-like pigmentation over the face (figure 1A–C).

Figure 1

(A and B) Multiple well-defined superficial moist erosions over dorsal aspect of hands, feet, forearm and face healing with postinflammatory hypopigmentation along with scars. (C) Hypertrichosis and melasma-like pigmentation over the face.

Skin biopsy …

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