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Colon cancer presenting as amyotrophic dermatomyositis
  1. Shing Fung Lee1,
  2. Yip Cheung Lam2,
  3. Siu Ming Mak2,
  4. Frank Chi Sing Wong1
  1. 1 Department of Clinical Oncology, Tuen Mun Hospital, New Territories West Cluster, Hong Kong, China
  2. 2 Department of Clinical Pathology, Tuen Mun Hospital, New Territories West Cluster, Hong Kong, China
  1. Correspondence to Dr Shing Fung Lee, Department of Clinical Oncology, Tuen Mun Hospital, Hong Kong, China; leesfm{at}ha.org.hk

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A 69-year-old woman presented to the medical outpatient clinic with a 1-month history of a non-pruritic rash that first affected her face, then her trunk and limbs. She had no arthralgia, myalgia or limb weakness. Examination revealed a heliotrope rash, shawl sign and Gottron papules (figure 1A, B and C). Antinuclear antibodies, myositis-specific autoantibody anti-SAE1 and myositis-associated autoantibody anti-Ro52 were detected, but C3 and C4 complements, and serum creatine phosphokinase levels were normal. Skin biopsy revealed interface dermatitis and perivascular inflammatory infiltrate, with an increase in dermal mucin …

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