Article Text

PDF
Giant variant of acquired reactive perforating collagenosis in diabetic nephropathy
  1. Muhammed Razmi T1,
  2. Debajyoti Chatterjee2,
  3. Davinder Parsad1
  1. 1 Department of Dermatology, Venereology, and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
  2. 2 Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
  1. Correspondence to Professor Davinder Parsad, Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India; parsad{at}me.com

Statistics from Altmetric.com

A woman in her 60s, with diabetic nephropathy (chronic kidney disease stage: 4/5), presented with 2 months history of intensely itchy papules over extensor aspects of her limbs, especially legs. Her serum creatinine levels had shown a rise from 2.7mg/dL to 3.5mg/dL during 2 months of the lesion onset. Her fasting blood sugar and glycated haemoglobin levels were 152mg/dL and 7.8%, respectively. Cutaneous examination revealed multiple crusted papules and plaques, largest measuring 2.5cm, with well-defined keratotic plugs at the centre (figure 1A). Histopathology of the lesion demonstrated cup-shaped invaginations in the epidermis enabling elimination of degenerated collagen fibres from the dermis (figure 1B). A diagnosis of acquired reactive perforating collagenosis …

View Full Text

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.