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Meningococcal sepsis and purpura fulminans: the surgical perspective
  1. Marvin E Morris1,
  2. John G Maijub1,
  3. Sarah K Walker1,
  4. Glenn P Gardner2,
  5. Riley G Jones3
  1. 1Department of Surgery, University of Louisville, Louisville, Kentucky, USA
  2. 2Department of Surgery, Valley Hospital and Medical Center, Spokane, Washington, USA
  3. 3Department of Surgery, University of Texas Medical Branch, Galveston, Texas, USA
  1. Correspondence to Dr Marvin Elston Morris, Department of Surgery, University of Louisville School of Medicine, 550 S Jackson St, Louisville, KY 40202, USA; dcmorris12{at}


Meningococcal sepsis and purpura fulminans is a rare but highly lethal disease process that requires a multidisciplinary team of experts to optimise morbidity and mortality outcomes due to the breadth of complications of the disease. The surgical perspective involves the critical care management which utilises all currently available measured outcomes of critical care management as well as experimental therapies. Limb loss is common, and is reflective of the high incidence of compartment syndrome compounded by the significant soft tissue loss secondary to purpura and limb ischaemia, presumptively due to digital microemboli. A multidisciplinary approach involving current standards in critical care and early surgical evaluation are important in improving patient outcomes and limb salvage.

  • Vascular Medicine
  • Infectious Diseases

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