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Secondary haemophagocytic lymphohistiocytosis (HLH) triggered by Salmonella typhi
  1. Navneet Arora1,
  2. Neeraj Singla2,
  3. Aleena Jain3,
  4. Prashant Sharma4,
  5. Navneet Sharma1
  1. 1 Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India
  2. 2 PGIMER, Chandigarh, India
  3. 3 Internal Medicine, Chandigarh, India
  4. 4 Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
  1. Correspondence to Dr Neeraj Singla, PGIMER, Chandigarh 29751, India; neerajsingladr{at}

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A 19-year-old woman with no significant medical history presented to the emergency room with high-grade fever (up to 103°F), generalised weakness, loose stools and vomiting for 4 days. She was pale on examination and had a blood pressure of 100/60 mm Hg, a pulse rate of 114 beats/min and maintained 97% of oxygen saturation on room air. Ultrasonography of the abdomen was suggestive of hepatosplenomegaly. Laboratory investigations revealed pancytopenia, serum ferritin of 1690 ng/mL, and bone marrow examination was suggestive of presence …

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  • Contributors NA: writing the original manuscript and patient care. NSingla: manuscript supervision, expert guidance and patient care. AJ: bone marrow imaging, reporting, figure legends. PS: bone marrow imaging, expert guidance and figure legends. NSharma: expert guidance and patient management.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.