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Non-alcoholic steatohepatitis in a Japanese obese child
  1. Toshihiko Kakiuchi,
  2. Yurie Sakata
  1. Pediatrics, Saga University Hospital, Saga, Japan
  1. Correspondence to Toshihiko Kakiuchi, Pediatrics, Saga University Hospital, Saga 849-8501, Japan; kakiucht{at}cc.saga-u.ac.jp

http://dx.doi.org/10.1136/postgradmedj-2020-138951

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    A 10-year-old boy was referred to our hospital because of liver dysfunction. His body mass index was 29.7; however, other physical findings were normal. He did not have any history of illness and was not taking any medication. His parents were obese and had fatty liver disease, but no hypertension or diabetes. His laboratory data were as follows: total bilirubin, 0.6 (normal range (NR) 0.3–1.2) mg/dL; aspartate aminotransferase, 253 (NR 14–33) IU/L; alanine aminotransferase, 588 (NR 3–20) IU/L; γ-glutamyl transferase, 186 (NR 7–23) IU/L; total cholesterol, 222 (NR 140–199) mg/dL; low-density lipoprotein, 151 (NR 60–119) mg/dL and triglyceride, 134 (NR 30–149) mg/dL. Abdominal ultrasonography (US) and abdominal CT revealed fatty liver, but no evidence of chronic hepatitis or …

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    Footnotes

    • Contributors As the lead author, TK was involved in all stages of patient management and wrote the manuscript. TK and YS performed the treatment. Both authors read and approved the final manuscript.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.