You are here

Article Text

Article menu
Download PDFPDF
Letter
Impaired ketone body utilisation as a cause of life-threatening ketoacidosis
  1. Jörn Oliver Sass1,2,
  2. Sarah C Grünert3
  1. 1 Research Group Inborn Errors of Metabolism, Department of Natural Sciences & Institute for Functional Gene Analytics (IFGA), Bonn-Rhein-Sieg University of Applied Sciences, Rheinbach, Germany
  2. 2 University College Dublin School of Biomolecular and Biomedical Science, Dublin, Ireland
  3. 3 Department of General Pediatrics, Adolescent Medicine and Neonatology, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany
  1. Correspondence to Professor Jörn Oliver Sass, Research Group Inborn Errors of Metabolism, Department of Natural Sciences & Institute for Functional Gene Analytics (IFGA), Bonn-Rhein-Sieg University of Applied Sciences, 53359 Rheinbach, Germany; joern.oliver.sass{at}h-brs.de

http://dx.doi.org/10.1136/postgradmedj-2021-139710

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    We read with great interest the review article by Bashir et al, which aimed to increase awareness of enhanced ketogenesis as a cause of potentially fatal ketoacidosis.1 While the authors presented diabetic ketoacidosis as the most common cause of this metabolic disturbance, they highlighted alcoholic ketoacidosis and starvation ketoacidosis as differential diagnoses which require a different treatment approach, for example, not to drive patients into hypoglycaemia by administration of insulin. In contrast, rare inborn errors of metabolism and endocrine disorders other than diabetes mellitus received only little attention …

    View Full Text

    Footnotes

    • Contributors JOS conceptualised the letter, and SCG contributed with original ideas and reviewed the letter prior to submission.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests JOS consults a medical diagnostic laboratory in the laboratory diagnostics of inborn errors of ketone body metabolism.

    • Provenance and peer review Not commissioned; internally peer reviewed.