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- biochemistry
- chemical pathology
- porphyria
- paediatric clinical genetics & dysmorphology
- paediatric endocrinology
- paediatric intensive & critical care
We read with great interest the review article by Bashir et al, which aimed to increase awareness of enhanced ketogenesis as a cause of potentially fatal ketoacidosis.1 While the authors presented diabetic ketoacidosis as the most common cause of this metabolic disturbance, they highlighted alcoholic ketoacidosis and starvation ketoacidosis as differential diagnoses which require a different treatment approach, for example, not to drive patients into hypoglycaemia by administration of insulin. In contrast, rare inborn errors of metabolism and endocrine disorders other than diabetes mellitus received only little attention …
Footnotes
Contributors JOS conceptualised the letter, and SCG contributed with original ideas and reviewed the letter prior to submission.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests JOS consults a medical diagnostic laboratory in the laboratory diagnostics of inborn errors of ketone body metabolism.
Provenance and peer review Not commissioned; internally peer reviewed.