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Collaborators Rory B G O’Sullivan, Medical Genetics BSc, MBChB, Royal Hallamshire Hospital, Glossop Road, Sheffield, United Kingdom, S10 2J.
Contributors KR and EO were involved in idea conception, writing and revising the final manuscript. DW created all visuals and made significant contributions to the final manuscript. All authors are responsible and accountable for the research.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent for publication Not required.
Provenance and peer review Not commissioned; externally peer reviewed.