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Spontaneous spinal epidural haematoma due to polypharmacy including multiple antiplatelet agents
  1. Takahide Wada1,
  2. Taku Harada2,3,
  3. Keiichiro Ikeda2,
  4. Juichi Hiroshige2
  1. 1 Department of Neurology, Showa University Koto Toyosu Hospital, Tokyo, Japan
  2. 2 General Medicine, Showa University Koto Toyosu Hospital, Tokyo, Japan
  3. 3 Diagnostic and Generalist Medicine, Dokkyo Medical University Hospital, Tochigi, Japan
  1. Correspondence to Taku Harada, Division of General Medicine, Showa Medical University Hospital, 1-5-8 Hatanodai, Shinawagawa-ku, Tokyo 142-5555, Japan; hrdtaku{at}

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An 84-year-old woman presented to the emergency department with sudden-onset severe low back pain and associated left leg numbness. The low back pain developed on waking up in the morning and was aggravated by movement. She denied any falls or trauma. Her medical history was significant for chronic kidney disease, diabetes, hypertension, myocardial infarction, peripheral arterial disease, Parkinson disease, spinal canal stenosis, lumbar spondylolisthesis and an overactive bladder. She was on 15 regular medications, including five antiplatelet agents (aspirin, clopidogrel, sarpogrelate, limaprost, alfadex and dipyridamole). The regimen was developed over time, with each specialist prescribing medication for each disease in the past. The regimen continued after her care was transitioned to a primary care centre. The muscle strength of both lower limbs progressed …

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  • Contributors According to the definition given by the International Committee of Medical Journal Editors (ICMJE), the following individuals qualify for authorship based on their substantial contributions to the manuscript’s intellectual content: Taku Harada and Juichi Hiroshige, conception and design; Takahide Wada and Keiichiro Ikeda, acquisition of data; Takahide Wada and Taku Harada, patient management and interpretation of data. Furthermore, Takahide Wada and Taku Harada have participated in writing the manuscript. All authors have read the manuscript and approved submission. All authors have reviewed and agree with the content of this manuscript.

  • Funding This study did not receive any funding.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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