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Is COVID-19 more severe in older men?
  1. Xiaopeng Liang1,2
  1. 1 Medicine, University of Hong Kong, Hong Kong, Hong Kong
  2. 2 National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Xicheng District, Beijing, China
  1. Correspondence to Dr Xiaopeng Liang, Medicine, University of Hong Kong, Hong Kong, Hong Kong; lxp9886{at}gmail.com

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In the past 3 months, the pandemic caused by COVID-19 has been a considerable threat facing the entire world, causing substantial morbidity and mortality. By 20 April 2020, a total of 2 285 210 cases of positive laboratory-confirmed COVID-19 cases had been reported worldwide, and 155 124 deaths had been documented in over 200 territories. The worldwide mortality rate is around 4.5%,1 although the actual mortality rate is probably lower due to undiagnosed cases. Previous studies on the severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV) showed that older men were at higher risk of coronavirus infection. Older men also seem to be more susceptible to COVID-19. Furthermore, patients older than 65 years with comorbidities have poorer outcomes. In a study of 1099 COVID-19 patients, the median age of patients with severe disease (173/1099) …

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